Primary Care
Jul 8, 2025

Start Smart: 5 Baseline Tests Your Primary-Care Doctor Recommends

Start Smart: 5 Baseline Tests Your Primary-Care Doctor Recommends

Why establishing a “baseline” matters

Baseline tests draw that map for your body, marking today’s coordinates so future readings can trace steady progress, early drift, or sudden detours. High blood pressure, prediabetes, silent kidney trouble, and fatty-liver changes rarely shout warnings; spotting them in data rather than in crisis is the surest, most compassionate gift you can give your future self.

Think of the five assessments below as a panoramic lens on your health. Together they sweep across cardiovascular, metabolic, renal, hepatic, hematologic, and immune territories, flagging risk years before it calcifies into disease.

1. Blood pressure and other vital metrics

What gets checked

  • Systolic and diastolic blood pressure (arm cuff)
  • Heart rate
  • Weight and body-mass index (BMI)
  • Waist circumference

Why it matters
Persistent systolic readings above 130 mm Hg double cardiovascular-mortality risk over ten years.² Even a ten-point creep raises stroke probability by 17 %. Waistlines over 35 inches for women or 40 inches for men predict a two-fold jump in type 2 diabetes risk.

Targets and timing

  • Blood pressure: aim for less than 120/80 mm Hg; repeat every one to two years if normal and at least yearly if elevated.
  • BMI: 18.5–24.9 kg/m² for most body types; check at every visit.
  • Waist circumference: below 35 in (women) or 40 in (men); check at every visit.

Proactive takeaway
If your numbers edge upward, try a 12-week experiment: add two brisk 20-minute walks per week and swap one processed-food meal for a rainbow plate heavy on plants and lean protein. Small shifts bend long-term curves.

2. Lipid panel (Cholesterol test)

What gets measured

  • Total cholesterol
  • LDL-C (“bad” cholesterol)
  • HDL-C (“good” cholesterol)
  • Triglycerides

A fast of eight to twelve hours gives the cleanest baseline, although non-fasting samples are acceptable in many low-risk adults.

Why it matters
Low-density lipoproteins seed arterial plaque. In the Framingham Offspring Study, every 39 mg/dL drop in LDL predicted a 37 % fall in coronary events.³

Key numbers

  • LDL-C: below 100 mg/dL for most adults, or below 70 mg/dL if you already have heart disease or diabetes.
  • HDL-C: above 50 mg/dL for women or 40 mg/dL for men.
  • Triglycerides: below 150 mg/dL.

Testing cadence
Check at least every five years from age 20. Re-draw annually if you have diabetes, hypertension, obesity, or a family history of early heart attack.

Proactive takeaway
Trade red meat for oily fish twice a week, sprinkle soluble-fiber oats into breakfast, and accumulate 150 minutes of moderate movement weekly. Many people see LDL fall 5–10 % within three months.

3. Hemoglobin A1C or fasting plasma glucose

What gets measured

  • Hemoglobin A1C: a three-month average of blood-sugar exposure.
  • Fasting plasma glucose (FPG): your blood sugar after an overnight fast.

Why it matters
The CDC estimates that 38 % of U.S. adults harbor prediabetes.⁴ Left alone, about one in ten of those people will convert to type 2 diabetes each year; lifestyle coaching that trims body weight by only seven percent cuts the conversion risk by 58 %.⁵

Diagnostic cut-points

  • A1C below 5.7 % is normal; 5.7–6.4 % signals prediabetes; 6.5 % or higher confirms diabetes.
  • FPG below 100 mg/dL is normal; 100–125 mg/dL signals prediabetes; 126 mg/dL or higher confirms diabetes.

Testing cadence
Screen every three years starting at age 35, or earlier and more often if you are overweight plus have hypertension, polycystic-ovary syndrome, a history of gestational diabetes, or a first-degree relative with diabetes.

Proactive takeaway
Distribute carbohydrates evenly throughout the day and pair starches with protein or healthy fat to blunt sugar spikes. A fifteen-minute walk after dinner can lower post-meal glucose by nearly one-third.

4. Comprehensive metabolic panel (CMP)

What gets measured

  • Electrolytes (sodium, potassium, chloride, bicarbonate)
  • Kidney function (creatinine and estimated glomerular filtration rate, eGFR)
  • Liver enzymes (ALT, AST) and bilirubin
  • Total protein and blood glucose

Why it matters
A persistent eGFR under 60 mL/min/1.73 m² predicts up to a sixteen-fold jump in end-stage kidney disease over a decade.⁶ Mildly elevated ALT or AST can reveal non-alcoholic fatty-liver disease, the fastest-growing cause of cirrhosis worldwide.

Targets and timing

  • Creatinine: roughly 0.6–1.3 mg/dL for most adults.
  • eGFR: 60 mL/min/1.73 m² or higher.
  • ALT: 7–56 U/L.
  • AST: 10–40 U/L.

Check at baseline, then yearly if you take kidney-active medications such as ACE inhibitors or NSAIDs, or if you live with diabetes, hypertension, or obesity.

Proactive takeaway
Hydration matters. Drinking a glass of water before each meal supports kidney filtration and complements blood-pressure control.

5. Complete blood count (CBC)

What gets measured

  • Hemoglobin and hematocrit (oxygen-carrying red cells)
  • Mean corpuscular volume (average red-cell size)
  • White-blood-cell count with differential
  • Platelet count

Why it matters
In adults over sixty, unexplained anemia links to a forty percent higher five-year mortality even after adjusting for other illnesses.⁷ Common culprits—iron deficiency, vitamin B12 deficiency, hidden bleeding, early kidney disease—are often correctable.

Healthy ranges (typical)

  • Hemoglobin: 12.0–15.5 g/dL in women; 13.5–17.5 g/dL in men.
  • White blood cells: 4.0–11.0 × 10⁹/L.
  • Platelets: 150–450 × 10⁹/L.

Testing cadence
Draw once at baseline, then whenever fatigue, heavy menses, chronic illness, or certain medications raise concern.

Proactive takeaway
If low hemoglobin pairs with low ferritin, combine plant-based iron sources (lentils, spinach) with vitamin C-rich foods to boost absorption up to four-fold.

Crafting your personal testing timeline

A trusted clinician weaves these single snapshots into a living story shaped by age, genetics, pregnancy status, medications, stress load, and social determinants. One patient may redraw lipids each year, another every three years. That is the magic of primary-care partnership: data meets context.

If you are still deciding which type of doctor fits your life philosophy, explore Morningside’s guide “Which Type of Primary Care Physician Is Best?”

Frequently asked questions

Do I need to fast for every blood test?
Only lipid panels and fasting plasma glucose require an eight- to twelve-hour fast. Hemoglobin A1C, CMP, and CBC do not.

What if my results sit just outside the normal range?
Normal reference intervals capture 95 % of a healthy population, so one in twenty healthy people will land slightly beyond the limits. Your doctor interprets results in the context of symptoms, other labs, and long-term trends before labeling anything abnormal.

How quickly can lifestyle changes move my numbers?
Blood pressure and fasting glucose can improve within weeks. Lipids often shift after six to twelve weeks of sustained habits, while anemia correction depends on cause and treatment plan.

Can I order these labs online?
Direct-to-consumer platforms exist, but partnering with a primary-care clinician ensures accurate interpretation, insurance guidance, and coordinated follow-up if anything looks off track.

The long-game payoff

Baseline testing is less about chasing perfect numbers than about owning your health trajectory. Each data point becomes a waypoint that guides tomorrow’s choices—nutrition tweaks, stress-management breakthroughs, or preventive medication when necessary. Data paired with compassionate guidance unlocks a life lived freely and fully.

References

  1. Benson T et al. Missed opportunities for disease prevention in primary care: a national study. J Gen Intern Med. 2023;38:801-809.
  2. SPRINT Research Group. A randomized trial of intensive versus standard blood-pressure control. N Engl J Med. 2015;373:2103-2116.
  3. Wilson PWF et al. Prediction of coronary heart disease using risk-factor categories. Circulation. 1998;97:1837-1847.
  4. Centers for Disease Control and Prevention. National Diabetes Statistics Report, 2023.
  5. Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002;346:393-403.
  6. Go AS et al. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med. 2004;351:1296-1305.
  7. Patel KV et al. Anemia prevalence and hemoglobin dynamics in older adults. Blood. 2009;113:4824-4831.

For professional medical advice, diagnosis, or treatment, always consult your doctor or other qualified health provider. In case of an emergency, call 911 immediately.

This blog post is for informational purposes only and does not constitute medical advice. Always consult a medical professional for personalized guidance and treatment.